Abu Dhabi launches newborn genetic screening programme

Abu Dhabi has rolled out a newborn genetic screening programme for Emirati nationals across several hospitals, to enable early detection and diagnosis of genetic conditions.

The Newborn Genetic Screening Programme offers whole genome sequencing to screen more than 815 treatable childhood genetic conditions, including metabolic disorders, immunodeficiencies, hematologic conditions, and rare diseases such as spinal muscular atrophy.

Using genomics and artificial intelligence (AI), the first phase of the programme has been implemented as a voluntary option at Kanad Hospital and Danat Al Emarat Hospital, in partnership with M42.

The initiative is planned to be expanded across all maternity hospitals to screen UAE nationals and children of Emirati mothers born in the emirate.

By collecting and testing cord blood samples at birth, with parental consent, healthcare providers can identify conditions that may not be apparent at birth but could significantly affect a child’s health if treatment is delayed.

Results are reported within 21 days, and parents will receive genetic counselling and be referred to multidisciplinary specialists if any actionable findings are identified.

“Through early detection, personalised care and strategic foresight, we are building a future of healthier generations and reinforcing Abu Dhabi’s position as a global leader in proactive, precision healthcare," said Dr. Noura Khamis Al Ghaithi, Undersecretary of the Department of Health – Abu Dhabi.

To support the rollout of the programme, DoH conducted a workshop to review the gene panel and patient journey with specialists from stakeholders across Abu Dhabi. DoH also collaborated with M42 to train 16 paediatricians and neonatologists across three maternity hospitals, Corniche Hospital, Danat Al Emarat and Kanad Hospital, on genetic counselling practices and the importance of newborn  genetic screening.

These initiatives aim to reduce the prevalence of genetic diseases, inform reproductive choices, facilitate access to early intervention, and empower families with vital health information, fostering a future where personalised, preventative healthcare is the standard.

The Newborn Genetic Screening Programme is one of several initiatives that have been made possible by the Emirati Genome Programme, such as the Premarital Screening Programme, harnessing the power of genomics and latest technologies to promote informed decisions. These efforts pave the way forward for more precise and effective treatments, ensuring the long-term health and wellbeing of future generations of Emiratis.